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About Us

home About Us> Members> Jung-Ae Kim, Ph.D.

Jung-Ae Kim, Ph.D.

Dr. Jung-Ae Kim

Dr. Jung-Ae Kim
Jung-Ae Kim, Ph.D.Senior Researcher

Personalized Genomic Medicine Research Center
@Korean Research Institute of Bioscience and Biotechnology (KRIBB)

  • Tel+82-42-879-8129
  • Fax+82-42-879-8119
  • E-mailjungaekim@kribb.re.kr

EDUCATION AND PROFESSIONAL CAREER

  • 2014 - present Senior Researcher, Epigenomics Research Center, Genome Institute, KRIBB, Daejeon, South Korea
  • 2013 - present Adjunct professor, Department of Functional Genomics, UST, Daejeon, South Korea
  • 2012 - 2014 Senior Researcher, Biomedical Genomics Research Center, KRIBB, Daejeon, South Korea
  • 2008 - 2012 Postdoctoral Associate, Laboratory of Chromatin Biology and Epigenetics (PI: C. David Allis), The Rockefeller University, New York, NY 10065, USA
  • 2002 - 2008 Ph.D. in Molecular and Cell Biology Program at Brandeis University (Advisor: James E. Haber), Waltham, MA 02453, USA
  • 1999 - 2002 Research Associate at National Creative Research Initiative Center for Cell Cycle Control (PI: Yeon-Soo Seo), Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, South Korea
  • 1997 - 1999 Master of Science in Biochemistry at Korea University (Advisor: Joon Kim), Seoul, South Korea
  • 1993 - 1997 Bachelor of Science in Biology at Korea University, Seoul, South Korea

HONORS AND AWARDS

  • 2012 Keystone Symposia Future of Science Fund Scholarship
  • 2009-2010 Women & Science Fellowship Award, Rockefeller University
  • 2004Awarded for a special travel fellowship for â??Meeting for DNA replication and genomic integrityâ?? held by Salk Institute/Cal. Tech

FUNDING SUPPORT

  • 2013-2016 Basic Science Research Program through the National Research Foundation of Korea (NRF)

PRESENTATIONS

  • 2014 KSMCB Epigenome Syposium (Dec. 2014) Hongchun, South Korea. Invited for an oral talk
  • 2014 CSHL Mechanisms and Models of Cancer (Aug. 2014) CSH, NY, USA.
  • 2013 BIEN 2013 (Aug. 2013) Seoul, South Korea. Invited for an oral talk
  • 2012 The Keystone Symposium on Chromatin Dynamics (Jan. 2012) Keystone, CO. USA.
  • 2010 7th 3R (Replication, recombination and repair) meeting in Japan (Oct. 2010) Selected for an oral presentation. Toyama, Japan.
  • 2007 FASEB summer research conferences: Chromatin and transcription. (Jul. 2007) Selected for an oral presentation. Snowmass village, CO, USA.
  • 2006 FASEB summer research conferences: Yeast chromosome structure, replication and segregation. (Aug. 2006) Indian wells, CA, USA.
  • The 14th annual conference for New England Bioscience Society of Koreans. (May 2006) Invited for an oral presentation. Boston, MA, USA.
  • 2005 FASEB summer research conferences: Chromatin and transcription. (Jul. 2005) Snowmass village, CO, USA.
  • Meeting for DNA replication and genomic integrity held by Salk institute/Cal. Tech. (Aug. 2004) Awarded for a special travel fellowship. La Jolla, CA, USA.
  • 2001 CSHL Eukaryotic DNA replication meeting. (Sep. 2001) Cold Spring Harbor, NY, USA

Publication List

  • Yang SJ, Park YS, Cho JH, Moon B, Ahn HJ, Lee JY, Xie Z, Wang Y, Pocalyko D, Lee DC, Sohn HA, Kang M, KJim JY, Kim E, Park KC*, Kim JA*, Yeom YI*. Regulation of hypoxia response by Flavin adenine dinucleotide-dependent modulation of HIF-1a protein stability. (2017) EMBO J, 36(8):1011-28. (* Co-corresponding authors)
  • Kim JA. Gut microbiome, a potent modulator of epigenetics in human diseases (2017) J. Bacteriology & Virology, 47(2);1-12.
  • Park YS, Kim DJ, Koo H, Jang SH, You YM, Cho JH, Yang SJ, Yu ES, Jung Y, Lee DC, Kim JA, Park ZY, Yeom YI, Park KC (2016) Oncotarget, 478(2):976-81.
  • Kim DJ, Park YS, Kang MG, You YM, Jung Y, Koo H, Kim JA, Kim MJ, Hong SM, Lee KB, Jan JJ, Park KC, Yeom YI. Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells (2015) Exp Cell Res, 336(1):119-29.
  • Lee DC, Sohn HA, Kang YK, Oh S, Lee KM, Kang M, Jang YJ, Yang SJ, Hong YK, Noh H, Kim JA, Kim DJ, Bae KH, Kim DM, Chung SJ, Yoo HS, Yu DY, Park ZY, Park KC, Yeom YI. A lactate-induced response to hypoxia (2015) Cell, 161(3):595-609.
  • Kim DJ, Park YS, Kim ND, Min SH, You YM, Jung Y, Koo H, Noh H, Kim JA, Yeom YI, Park KC. A novel pyruvate kinase M2 activator compound that suppresses lung cancer cell viability under hypoxia (2014) Mol Cells, 38(4):373-9.
  • Kim J*, Kim JA*, McGinty RK, Nguyen UT, Muir TW, Allis CD, Roeder RG. The n-SET domain of Set1 regulates H2B ubiquitylation-dependent H3K4 methylation. (2013) Mol. Cell, 49 (6):1121-33 (*These authors equally contributed to this paper.)
  • Kim JA, Hsu J, Smith MM, Allis CD. Mutagenesis of pair-wise combinations of histone amino-terminal tails uncover novel phenotypes in budding yeast (2012) Proc. Nat. Acad. Sci., 109(15):5779-84
  • Li J, Coic E, Lee K, Lee CS, Kim JA, Wu Q, Haber JE. Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1. (2012) PLoS Genet., 8:e1002630.
  • Kim JA, Hicks WM, Haber JE. Protein phosphatase Pph3, Ptc2, and Ptc3 play redundant roles in DNA double strand break repair by homologous recombination. (2011) Mol. Cell Biol., 31(3):507-16.
  • Joo YJ, Kim JA, Baek JH, Seong KM, Han KD, Song JM, Choi JY, Kim J. Cooperative regulation of ADE3 transcription by Gcn4p and Bas1p in Saccharomyces cerevisiae. (2009) Eukaryotic Cell, 8:1268-77.
  • Kim JA, Haber JE. Yeast chromatin assembly factors CAF-1 and Asf1 play overlapping roles in deactivating the DNA damage checkpoint when DNA repair is complete. (2009) Proc. Nat. Acad. Sci. 106(4):1151-6.
  • Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X.TH Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. (2007) Cell. 130(3):499-511.
  • Kim JA, Kruhlak M, Dotiwala F, Nussenzweig A, Haber JE. Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. (2007) J. Cell Biol. 178(2):209-18.
  • Keogh MC*, Kim JA*, Downey M*, Fillingham J., Chowdhury D, Harrison JC, Onishi M, Datta M, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ. A phosphatase complex that dephosphorylates gamma H2AX regulates DNA damage checkpoint recovery. (2006) Nature. 439(7975): 497-501.
    (* These authors equally contributed to this paper. Reviewed in News & Views of Nature (2006) 439(7075): 406-7)
  • Bae SH, Bae KH, Kim JA, Seo YS. RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes. (2001) Nature. 412(6845): 456-461.
  • Bae SH, Kim JA, Choi E, Lee KH, Kang HY, Kim HD, Kim JH, Bae KH, Cho Y, Park C, Seo YS. Tripartite structure of Saccharomyces cerevisiae Dna2 helicase/endonuclease. (2001) Nucleic Acids Res. 29(14): 3069-3079.
  • Lee KH, Kim DW, Bae SH, Kim JA, Ryu GH, Kwon YN, Kim KA, Koo HS, Seo YS. The endonuclease activity of the yeast Dna2 enzyme is essential in vivo. (2000) Nucleic Acids Res. 28(15): 2873-2881.
  • Lee JY, Bae YB, Kim JA, Song JM, Choe M, Kim IK, Kim J. (1999) Site directed saturation mutagenesis of yeast Gcn4p on codon 242. J. Microbiol. & Biotech. 9:122-125.